| Description | Imatinib carbaldehyde (also known as CGP-57148B carbaldehyde) is a compound derived from Imatinib, an inhibitor of the ABL protein. Imatinib carbaldehyde binds to the IAP ligand with the assistance of a linker, resulting in the formation of SNIPER[1]. |
| Synonyms | CGP-57148B carbaldehyde, STI571 carbaldehyde, PROTAC ABL binding moiety 1 |
| molecular weight | 507.59 |
| Molecular formula | C29H29N7O2 |
| CAS | 1436868-85-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. |