| Description | IDT307, an analog of the organic cation MPP+, serves as a specific fluorescent substrate for DAT, identified as APP+. |
| In vitro | IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1]. IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1]. |
| molecular weight | 340.2 |
| Molecular formula | C14H17IN2 |
| CAS | 1141-41-9 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018. |