| Description | ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO). |
| In vitro | ICI 211965 decreases the leakage of lactate dehydrogenase (LD). The lipid peroxidation at concentrations related to its antioxidative effect and not to its 5-1ipoxygenase-inhibiting effect[1]. |
| Synonyms | ZM-211965 |
| molecular weight | 389.51 |
| Molecular formula | C24H23NO2S |
| CAS | 129424-08-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Crawley GC, et al. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem. 1992 Jul 10;35(14):2600-9. |