| Description | ICI 198615, a novel, potent and selective peptide leukotriene antagonist, may be useful for the the treatment of allergic diseases. |
| Synonyms | ZM-198615, ICI-198,615, ZM 198615, ICI198615, ICI-198615 |
| molecular weight | 548.61 |
| Molecular formula | C28H28N4O6S |
| CAS | 104448-53-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Uchida Y, Hamada M, Kameyama M, Ohse H, Nomura A, Hasegawa S, Hirata F. ET-1 induced bronchoconstriction in the early phase but not late phase of anesthetized dogs is inhibited by indomethacin and ICI 198615. Biochem Biophys Res Commun. 1992 Mar 31;183(3):1197-202. PubMed PMID: 1567397. 2. Smith EF 3rd, Slivjak MJ. ICI 198615 is an antagonist of leukotriene C4, leukotriene D4 and leukotriene E4 vasopressor responses in the conscious rat. Pharmacology. 1990;41(2):57-66. PubMed PMID: 2175920. |