Description | Ibotenic acid (RS-42358-197) has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors. |
In vitro | Ibotenic acid对皮层神经元具有毒性,当暴露时间为5分钟时,以乳酸脱氢酶释放到培养基中的量来衡量,其半数有效浓度(EC50)为77.3 μM[1]。 |
Synonyms | (+/-)-Ibotenic acid, DL-Ibotenic acid, Ibotenate, 鹅膏氨酸, (RS)-Ibotenic acid |
molecular weight | 158.11 |
Molecular formula | C5H6N2O4 |
CAS | 2552-55-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 5 mg/mL (31.62 mM), Sonication is recommended. H2O: 5 mg/mL (31.62 mM), Sonication and heating are recommended. |
References | 1. Zinkand WC, et al. Ibotenic acid mediates neurotoxicity and phosphoinositide hydrolysis by independent receptormechanisms. Mol Chem Neuropathol. 1992 Feb-Apr;16(1-2):1-10. |