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Ibotenic acid

CAS No.: 2552-55-8

Ibotenic acid (RS-42358-197) has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.
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Description Ibotenic acid (RS-42358-197) has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.
In vitro Ibotenic acid对皮层神经元具有毒性,当暴露时间为5分钟时,以乳酸脱氢酶释放到培养基中的量来衡量,其半数有效浓度(EC50)为77.3 μM[1]。
Synonyms (+/-)-Ibotenic acid, DL-Ibotenic acid, Ibotenate, 鹅膏氨酸, (RS)-Ibotenic acid
molecular weight 158.11
Molecular formula C5H6N2O4
CAS 2552-55-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 5 mg/mL (31.62 mM), Sonication is recommended. H2O: 5 mg/mL (31.62 mM), Sonication and heating are recommended.
References 1. Zinkand WC, et al. Ibotenic acid mediates neurotoxicity and phosphoinositide hydrolysis by independent receptormechanisms. Mol Chem Neuropathol. 1992 Feb-Apr;16(1-2):1-10.