| Description | HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease. |
| Target activity | HCV NS3/4A protease:1.0 μmol/L (IC50) |
| Synonyms | HZ1157, DHFR-inhibitor |
| molecular weight | 232.28 |
| Molecular formula | C12H16N4O |
| CAS | 1009734-33-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (43.05 mM) |
| References | 1. Yu Y, et al. Discovering novel anti-HCV compounds with inhibitory activities toward HCV NS3/4A protease. Acta Pharmacol Sin. 2014 Aug;35(8):1074-81 |