| Description | hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases. |
| Target activity | PL (human):1.7 μM, Pancreatic lipase:1.63 μM |
| molecular weight | 443.11 |
| Molecular formula | C19H11Cl4NO3 |
| CAS | 24900-61-6 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (124.12 mM) |
| References | 1. Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413 |