| Description | hPL-IN-1 is a potent reversible pancreatic lipase (PL) inhibitor (IC50=1.86 μM) that can be used to study obesity-related diseases. |
| Target activity | Pancreatic lipase:1.86 μM |
| molecular weight | 410.2 |
| Molecular formula | C19H11Cl2F2NO3 |
| CAS | 2387374-26-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (121.89 mM) |
| References | 1. Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413. |