| Description | HOE-S 785026 trihydrochloride is a live cell labeling dye that binds nucleic acids by binding to the minor groove in DNA double strands. HOE-S 785026 trihydrochloride tends to bind to A/T-rich DNA strands (fluorescence is significantly enhanced by A/T-rich double-stranded DNA).HOE-S 785026 trihydrochloride crosses cell membranes and binds to living or immobilized cells.The fluorescence intensity of HOE-S 785026 trihydrochloride increases as the pH of the solution increases. HOE-S 785026 trihydrochloride crosses cell membranes and binds to living or immobilized cells. trihydrochloride fluorescence intensity increases as the pH of the solution is increased. |
| Synonyms | meta-Hoechst trihydrochloride, Meta-Hoechst trihydrochloride, HOE-S 785026 trihydrochloride (132869-83-1 free base) |
| molecular weight | 533.88 |
| Molecular formula | C25H27Cl3N6O |
| CAS | 2320308-12-9 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 47.3 mg/mL (88.60 mM), Sonication and heating are recommended. |
| References | 1. Parkinson JA, et al. Molecular design of DNA-directed ligands with specific interactions: solution NMR studies of the interaction of a m-hydroxy analogue of Hoechst 33258 with d(CGCGAATTCGCG)2. Biochemistry. 1994 Jul 19;33(28):8442-52. |
HOE-S 785026 trihydrochloride
CAS No.: 2320308-12-9
HOE-S 785026 trihydrochloride is a live cell labeling dye that binds nucleic acids by binding to the minor groove in DNA
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