Description | HMN-154 is a novel benzenesulfonamide anticancer compound. It is able to interact with NF-YB and interrupt the binding of NF-Y heterotrimer to DNA. |
Target activity | KB:0.0026 μg/mL, Colon38 cells:0.003 μg/mL |
Synonyms | HMN154 |
molecular weight | 366.43 |
Molecular formula | C20H18N2O3S |
CAS | 173528-92-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 15 mg/mL (40.94 mM) |
References | 1. Tanaka H., et al. Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. Mol Pharmacol. 1999 Feb;55(2):356-63. |