| Description | HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals. |
| In vitro | HKOH-1 shows absorption peaks at 500 nm. In absence of ? OH, HKOH-1 is non-fluorescent[1]. HKOH-1r (0.1-50 μM; 24 h) shows negligible or no cytotoxicity in both RAW264.7 cells and Hela cells[1]. HKOH-1r (5 μM; 30 min) detects endogenous ? OH in the flow cytometry platform in RAW264.7 cells[1]. |
| molecular weight | 745.08 |
| Molecular formula | C26H12Cl2I2O6 |
| CAS | 2031170-96-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Xiaoyu Bai, et al. HKOH-1: A Highly Sensitive and Selective Fluorescent Probe for Detecting Endogenous Hydroxyl Radicals in Living Cells. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12873-12877. |