| Description | HKOCl-4m is a rhodol-based fluorescent probe designed for the specific and deliberate targeting of mitochondria, enabling the monitoring of mitochondrial hypochlorous acid (HOCl). |
| In vitro | HKOCl-4m (5 μM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1]. |
| molecular weight | 1153.97 |
| Molecular formula | C63H61BrCl2N3O7P |
| CAS | 2031170-88-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Xiaoyu Bai, et al. HKOCl-4: a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid in living cells and tissues. Org. Chem. Front, 2020. |