| Description | HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM). |
| In vitro | HIV-1 Nef-IN-1 降低COS7细胞的存活率，其细胞抑制率为63.2%。 |
| Target activity | HIV-1 (Nef):6.7 μM (Kd) |
| molecular weight | 264.32 |
| Molecular formula | C18H16O2 |
| CAS | 13728-56-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (189.16 mM) |
| References | 1. Stéphane Betzi, et al. Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19256-61. |