| Description | Hexafluronium bromide is a neuromuscular blocker and nicotinic acetylcholine receptor antagonist used in anesthesiology to prolong and enhance the skeletal muscle relaxation of succinylcholine during surgery. |
| Synonyms | Mylaxen, Hexafluorenium bromide, Milaxen, Hexafluorenium dibromide, Esafluronio bromuro |
| molecular weight | 582.649 |
| Molecular formula | C36H42BrN2 |
| CAS | 317-52-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Britton RM, Figueroa M. Hexafluorenium bromide: current status and a review. Anesth Analg. 1973 Jan-Feb;52(1):100-5. Review. PubMed PMID: 4567515. 2. Radnay PA, Badola RP, Dalsania A, El-Gaweet EI, Duncalf D. Prevention of suxamethonium-induced changes in serum potassium concentration by hexafluorenium. Is their combined use justified? Br J Anaesth. 1979 May;51(5):447-51. PubMed PMID: 444345. 3. Radnay PA, El-Gaweet ES, Novakovic M, Badola R, Cizmar S, Duncalf D. Prevention of succinylcholine induced hyperkalemia by neurolept anesthesia and hexafluorenium in anephric patients. Anaesthesist. 1981 Jul;30(7):334-7. PubMed PMID: 6455928. 4. Scaf AH, Langendijk JW. The desensitizing interaction of hexafluorenium with the cholinergic receptor in the diaphragm of the rat. Arch Int Pharmacodyn Ther. 1977 Feb;225(2):196-207. PubMed PMID: 849069. |