PeptideDB

Hemokinin 1 (human) acetate(491851-53-7 free base)

CAS No.:

Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 recep
Sales Email:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Description Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
Target activity NK1: 1.8 nM, NK2: and 480 nM, NK3:370 nM
molecular weight 1245.45
Molecular formula C56H88N14O16S
Storage keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility H2O: Insoluble DMSO: Insoluble
References 1. Bellucci et al (2002) Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br.J.Pharmacol. 135 266 PMID: 2. Kurtz et al (2002) Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene 296 205 PMID: