| Description | Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink. |
| In vivo | Haematoxylin和曙红染色是最常用的组织学染色法之一。Hematoxylin (Hydroxybrazilin)是一种能够与某些金属离子形成强烈有色络合物的化合物,尤其能够与Fe(III) 和Al(III)盐以及一种组织学着色剂络合。 |
| Target activity | Aβ42 fibrillogenesis:1.6 µM (IC50) |
| Synonyms | 苏木精, Hydroxybrazilin, Natural Black 1, Haematoxylin |
| molecular weight | 302.28 |
| Molecular formula | C16H14O6 |
| CAS | 517-28-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 75 mg/mL (248.11 mM), Sonication is recommended. Ethanol: 57 mg/mL (188.6 mM) H2O: 56 mg/mL (185.3 mM) |
| References | 1. Godwin A, J Pharm Clin Sci, 2011, 1, 24-34. |
| Citations | 1. Li H, Pang B, Nie B, et al. Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis. Immunopharmacology and Immunotoxicology. 2022: 1-9. 2. Zhang M, Hao Z, Wu J, et al.Curcumin ameliorates traumatic brain injury via C1ql3-mediated microglia M2 polarization.Tissue and Cell.2023: 102164. |