| Description | Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV. |
| In vitro | Helioxanthin 和 Helioxanthin derivative 5-4-2 在 HepG2.2.15 细胞中显示出强效的抗 HBV 活性，EC50 分别为 1 和 0.08 microM[2]。 |
| Target activity | HBV:0.08 μM |
| Synonyms | Helioxanthin 5-4-2 |
| molecular weight | 347.32 |
| Molecular formula | C20H13NO5 |
| CAS | 203935-39-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (86.38 mM), Sonication is recommended. |
| References | 1. Yeo H, et al. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27;48(2):534-46. 2. Li Y, et al. Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative. Antivir Chem Chemother. 2005;16(3):193-201. |