| Description | HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor with IC50 values of 0.844 nM for FLT3 and 30.0 nM for HDAC1. It effectively suppresses MV4-11 cell proliferation with an IC50 of 92 nM, induces apoptosis, and arrests the cell cycle in MV4-11 cells. This compound is applied in acute myeloid leukemia (AML) research [1]. |
| molecular weight | 529.42 |
| Molecular formula | C25H26Cl2N6O3 |
| CAS | 2920046-95-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |