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hCAIX-IN-15

CAS No.: 2849348-43-0

hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, e
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Description hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1].
In vitro hCAIX-IN-15(化合物12i;48小时处理)对于肾癌(UO-31)、乳腺癌(MDA-MB-468)和非小细胞肺癌(HOP-92)细胞系展现出最佳的细胞毒性,相应地其GI%分别为20%、17%和16% [1]。
Target activity CA IX (human):38.8 nM (Ki)
molecular weight 411.41
Molecular formula C18H14FN7O2S
CAS 2849348-43-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year