| Description | hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1]. |
| In vitro | hCAIX-IN-15(化合物12i;48小时处理)对于肾癌(UO-31)、乳腺癌(MDA-MB-468)和非小细胞肺癌(HOP-92)细胞系展现出最佳的细胞毒性,相应地其GI%分别为20%、17%和16% [1]。 |
| Target activity | CA IX (human):38.8 nM (Ki) |
| molecular weight | 411.41 |
| Molecular formula | C18H14FN7O2S |
| CAS | 2849348-43-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |