| Description | hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1]. |
| In vitro | hAChE-IN-2（化合物21）（1-10 μM）在转染野生型tau蛋白的SH-SY5Y细胞中表现出明显的神经保护作用[1]。 |
| Target activity | AChE (human):0.71 μM |
| molecular weight | 394.44 |
| Molecular formula | C22H23FN4O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |