| Description | HA-100 is an inhibitor of protein kinase |
| Target activity | PKG:4 μM , PKC:12 μM, PKC:6.5 μM (Ki), PKA:8 μM , MLCK:240 μM , MLCK:61 μM (Ki) |
| molecular weight | 277.34 |
| Molecular formula | C13H15N3O2S |
| CAS | 84468-24-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 150 mg/mL (540.85 mM) |
| References | 1. Hagiwara M , Inagaki M , Watanabe M , et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives.[J]. Molecular Pharmacology, 1987, 32(1):7. |
| Citations | 1. Sun L, Sun L, Li X, et al. A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae. Frontiers in cellular and infection microbiology. 2022: 1341. |