| Description | GW-695634, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. |
| Synonyms | GW5634, GW695634, GW-5634G, GW-5634 |
| molecular weight | 574.43 |
| Molecular formula | C26H21Cl2N3O6S |
| CAS | 457635-65-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. De Serres M, Bowers G, Boyle G, Beaumont C, Castellino S, Sigafoos J, Dave M, Roberts A, Shah V, Olson K, Patel D, Wagner D, Yeager R, Serabjit-Singh C. Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism. Xenobiotica. 2011 Jun;41(6):464-75. doi: 10.3109/00498254.2011.560295. PubMed PMID: 21370990. 2. de Serres M, Moss L, Sigafoos J, Sefler A, Castellino S, Bowers G, Serabjit-Singh C. The disposition and metabolism of GW695634: a non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS. Xenobiotica. 2010 Jun;40(6):437-45. doi: 10.3109/00498251003770578. PubMed PMID: 20380622. 3. Boone LR. Next-generation HIV-1 non-nucleoside reverse transcriptase inhibitors. Curr Opin Investig Drugs. 2006 Feb;7(2):128-35. Review. PubMed PMID: 16499282. |