| Description | Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes. |
| Synonyms | 胍氯酚, VATENSOL |
| molecular weight | 263.12 |
| Molecular formula | C9H12Cl2N4O |
| CAS | 5001-32-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 2.63 mg/ml (10 mM), Sonication is recommended. |
| References | 1. SINNIAH R, GATENBY PB. CLINICOPHARMACOLOGICAL ASSESSMENT OF THE NEW ANTI-HYPERTENSIVE COMPOUND GUANOCLOR (VATENSOL). Ir J Med Sci. 1965 Mar;471:111-24. PubMed PMID: 14295356. 2. BENDER S. TO-DAY'S DRUGS. GUANOCLOR. Br Med J. 1964 Jul 25;2(5403):238-9. PubMed PMID: 14150915; PubMed Central PMCID: PMC1817852. 3. Mackinnon J, el-Baz LM. A comparison of guanoclor and methyldopa in the treatment of severe hypertension. Br J Clin Pract. 1971 Mar;25(3):135-7. PubMed PMID: 4929159. 4. Mehta AB, Biswas AK, Pinto IJ, Sheth UK. Clinical assessment of the new antihypertensive Compound--1029 (Vatensol)--Guanoclor. Indian Heart J. 1967 Oct;19(4):322-8. PubMed PMID: 4870898. |