| Description | GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy. |
| molecular weight | 506.98 |
| Molecular formula | C21H19ClN4O5S2 |
| CAS | 2181665-31-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |