| Description | GSK-A is a Histone Lysine Methyltransferase EZH2 inhibitor. |
| Synonyms | GSK A |
| molecular weight | 379.46 |
| Molecular formula | C21H25N5O2 |
| CAS | 923894-97-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Fraley KJ, Abberley L, Hottenstein CS, Ulicne JJ, Citerone DR, Szapacs ME. The Gyrolab™ immunoassay system: a platform for automated bioanalysis and rapid sample turnaround. Bioanalysis. 2013 Jul;5(14):1765-74. doi: 10.4155/bio.13.145. PubMed PMID: 23862708. 2. Cheng Z, Zhang J, Liu H, Li Y, Zhao Y, Yang E. Central nervous system penetration for small molecule therapeutic agents does not increase in multiple sclerosis- and Alzheimer's disease-related animal models despite reported blood-brain barrier disruption. Drug Metab Dispos. 2010 Aug;38(8):1355-61. doi: 10.1124/dmd.110.033324. Epub 2010 Apr 28. PubMed PMID: 20427691. 3. Fries HE, Aiello M, Evans CA. Use of a variably sensitive selected reaction monitoring method to extend the linear dynamic range for quantitative high-performance liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(3):369-74. PubMed PMID: 17206741. |