| Description | GPI-1485 (GM1485) (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke. |
| In vitro | GPI-1485 在正常人类真皮成纤维细胞（NHDF）中诱导了细胞重编程和神经细胞诱导[1]。 |
| In vivo | GPI-1485（5 mg/kg；腹腔注射；每日一次，持续6周）显著促进了大鼠的长期神经恢复。 |
| Synonyms | GM1485 |
| molecular weight | 241.28 |
| Molecular formula | C12H19NO4 |
| CAS | 186268-78-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 95 mg/mL (393.73 mM), Sonication is recommended. |
| References | 1. Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90(7):1413-23. |