| Description | GnRH Associated Peptide (GAP) (1-13), human Acetate was found to be a potent inhibitor of prolactin secretion and to stimulate the release of gonadotropins. Active immunization with peptides corresponding to GAP sequences led to greatly increased prolactin secretion. |
| In vivo | GAP被发现是一种强效的抑制催乳素分泌的抑制剂,并能在大鼠脑垂体细胞培养中刺激促性腺激素的释放。使用与GAP序列相对应的肽进行主动免疫,导致兔子催乳素分泌显著增加。 |
| Synonyms | GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base), GnRH Associated Peptide (1-13), Acetate(human) (100111-07-7 Free base) |
| molecular weight | 1552.63 |
| Molecular formula | C67H105N15O27 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 70 mg/mL (46.90 mM) H2O: insoluble |
| References | 1. Károly, Nikolics, Anthony, et al. A prolactin-inhibiting factor within the precursor for human gonadotropin-releasing hormone[J]. Nature, 1985, 316(6028):511 - 517. |