| Description | Glycyl-glutamine (Glycyl-L-glutamine monohydrate) is an inhibitory neuropeptide derived from beta-endorphin. |
| In vivo | 给予乙烯基麻醉的大鼠甘氨酰-L-谷氨酰胺一水合物(gly-L-gln),并在beta-End-(1-31)注射前使用。gly-L-gln还显著减弱了beta-End-(1-31)的呼吸抑制效应,有效抑制了beta-End-(1-31)引起的低氧血症和高碳酸血症[1]。 |
| Synonyms | Glycyl-L-glutamine monohydrate, 甘氨酰-L-谷氨酰胺一水合物, Glycyl-L-glutamine, Glycylglutamine |
| molecular weight | 203.2 |
| Molecular formula | C7H13N3O4 |
| CAS | 13115-71-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 62.5 mg/mL (307.58 mM), Sonication is recommended. |
| References | 1. Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8 2. Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8. |