| Description | Glutaminyl Cyclase Inhibitor 3, a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor (IC50: 4.5 nM). It significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions. |
| Target activity | GC (human):4.5 nM |
| molecular weight | 468.61 |
| Molecular formula | C24H32N6O2S |
| CAS | 2092921-50-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hoang VH, et al. Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design. J Med Chem. 2017 Mar 23;60(6):2573-2590. |
Glutaminyl Cyclase Inhibitor 3
CAS No.: 2092921-50-9
Glutaminyl Cyclase Inhibitor 3, a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibit
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