| Description | Germinone A (3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one) is a novel potent agonist of HTL/KAI2, stimulating activity for Arabidopsis seed germination, has antitumor activity in multiple types of carcinomas. |
| Synonyms | 3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one |
| molecular weight | 311.29 |
| Molecular formula | C17H13NO5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 22.5 mg/mL (72.28 mM) |
| References | 1. Li Q Q , Hsu I , Sanford T , et al. Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M[J]. Cellular & Molecular Life Sciences, 2017. 2. Borges S , EA Perez, EA Thompson, et al. Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.[J]. Molecular Cancer Therapeutics, 2015, 14(6). |