| Description | 1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance protein (MDR)-mediated efflux mechanisms. |
| Synonyms | 7-O-Methylapigenin, Puddumetin, Apigenin 7-methyl ether, 芫花素 |
| molecular weight | 284.26 |
| Molecular formula | C16H12O5 |
| CAS | 437-64-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble H2O: <1 mg/mL (Insoluble) DMSO: 52 mg/mL (182.9 mM) |
| References | 1. Yuan G , Fen L , Lei F , et al. Genkwanin Inhibits Proinflammatory Mediators Mainly through the Regulation of miR-101/MKP-1/MAPK Pathway in LPS-Activated Macrophages[J]. PLoS ONE, 2014, 9(5):e96741-. |