| Description | GEM144 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, blocks the cell cycle in G1/S phase and induces apoptosis. |
| molecular weight | 461.55 |
| Molecular formula | C28H31NO5 |
| CAS | 2487526-28-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |