| Description | (-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM. |
| Synonyms | (-)-gallocatechin-3-O-gallate, (-)-Gallocatechol gallate, 没食子儿茶素没食子酸酯, Gallocatechin gallate |
| molecular weight | 458.37 |
| Molecular formula | C22H18O11 |
| CAS | 4233-96-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 82 mg/mL (178.9 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble |
| References | 1. Ko CH,et al. Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism. J Agric Food Chem. 2009 Aug 26;57(16):7293-7. 2. Ikeda I,et al. Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. J Agric Food Chem. 2003 Dec 3;51(25):7303-7. 3. Zhao, Ming, et al. GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein. Nature Communications . 12.1 (2021): 1-14. |
| Citations | 1. Zhao, Ming, et al. GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein. Nature Communications. 2021 Apr 9;12(1):2114. doi: 10.1038/s41467-021-22297-8. 2. Xiao T, Cui M, Zheng C, et al. Both Baicalein and Gallocatechin Gallate Efficaciously Inhibit SARS-CoV-2 Replication by Targeting Mpro and Sepsis in Mice. Inflammation. 2021: 1-13. 3. Chen J, Zhou X, Fu L, et al.Natural Product-Based Screening for Lead Compounds Targeting SARS CoV-2 Mpro[J]. Pharmaceuticals, 2023, 16(5): 767..Pharmaceuticals.2023, 16(5): 767. |