| Description | GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective inhibitor of cyclin G associated kinase (GAK) with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride can also bind to RIPK2. |
| In vitro | GAK inhibitor 49 (compound 49) hydrochloride shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC 50 s of 28, 63 and >100μM, respectively [1]. |
| molecular weight | 406.86 |
| Molecular formula | C20H23ClN2O5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |