| Description | GA3-AM is an acetoxymethyl-modified erythromycin derivative that binds to the gibberellin-insensitive dwarf 1 (GID1) receptor, an inducible split recombinase system. |
| In vitro | GA3-AM 是植物激素赤霉酸的细胞渗透类似物，可作为化学二聚化剂或化学诱导剂，能已与雷帕霉素二聚化系统和 CRISPR/Cas9 激活剂结合使用，用于 CRISPR/Cas9 激活剂功能的时间控制，从而实现多个基因的时间调控[1]。 |
| Synonyms | GA3 AM, GA3AM |
| molecular weight | 418.44 |
| Molecular formula | C22H26O8 |
| CAS | 1373154-68-7 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 1 mg/mL (2.39 mM), Sonication is recommended. |
| References | 1. Weikang Sun, et al. Residue analysis of gibberellic acid isomer (iso-GA3) in brewing process and its toxicity evaluation in mice. Regul Toxicol Pharmacol. 2020 Feb;110:104514. 2. Miyamoto T, DeRose R, Suarez A, Ueno T, Chen M, Sun TP, Wolfgang MJ, Mukherjee C, Meyers DJ, Inoue T. Rapid and orthogonal logic gating with a gibberellin-induced dimerization system. Nat Chem Biol. 2012 Mar 25;8(5):465-70. |