Description | Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. |
Synonyms | ICI 182780 R enantiomer, ZD 9238 R enantiomer, ZM 182780 R enantiomer, Fulvestrant R enantiomer |
molecular weight | 606.77 |
Molecular formula | C32H47F5O3S |
CAS | 1807900-80-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex?): catalyst control over C-C bond formation. Chem Commun (Camb). 2015 Oct 14;51(80):14866-8. 2. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6. |