| Description | Frunevetmab (NV-02), a felinized monoclonal antibody targeting nerve growth factor (NGF), exhibits a high affinity with a dissociation constant (Kd) of 20 pM and has been demonstrated to effectively mitigate osteoarthritis (OA) pain in cats [1] [2]. |
| In vitro | Frunevetmab（NV-02）具有高亲和力和高效能，可中和神经生长因子（NGF），且不与补体结合[2]。 |
| In vivo | Frunevetmab（1.0-2.8mg/kg；皮下注射；第0、28及56天）在自然发生骨关节炎疼痛及相关活动障碍和残疾的猫中表现出有效治疗作用[1]。 |
| Synonyms | NV-02 |
| molecular weight | N/A |
| CAS | 1708936-80-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years |