| Description | FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM). |
| In vitro | FR-190809 inhibits foam cell formation (IC50: 215 nM)[1]. |
| molecular weight | 603.73 |
| Molecular formula | C29H34FN3O6S2 |
| CAS | 215589-63-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Tanaka A, et al. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands. J Med Chem. 1998 Oct 22;41(22):4408-20. |