| Description | Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. |
| In vitro | Formycin A ?antagonizes Zidovudine (AZT; a dideoxynucleoside chain terminator). |
| Target activity | HIV-1:10 μM （EC50） |
| Synonyms | NSC 102811 |
| molecular weight | 267.24 |
| Molecular formula | C10H13N5O4 |
| CAS | 6742-12-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63. 2. Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). |