| Description | Foravirumab (CR4098) is a monoclonal antibody targeting antigenic site III of the rabies virus glycoprotein [1]. |
| In vitro | Foravirumab(CR4098)能够识别位于抗原位点III的表位,并能绑定在PER.C6细胞上表达的变异糖蛋白(N336D)。它表现出与CR57类似的中和效力和广谱性,同时也能中和CR57的逃逸变异株[1]。 |
| In vivo | Foravirumab(CR4098;10、20和40 IU/kg)在携带天然狂犬病病毒的叙利亚仓鼠中能有效预防致命的病毒感染[1]。 |
| Synonyms | CR4098 |
| molecular weight | N/A |
| CAS | 944548-38-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years | Shipping with blue ice. |