| Description | Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence. The hydrophilic PEG spacer increases solubility in aqueous media. |
| molecular weight | 1212.3 |
| Molecular formula | C67H69N7O15 |
| CAS | 2055042-82-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550. 2. Harrison E, Coulter JA, Dixon D. Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker. Nanomedicine (Lond). 2016 Apr;11(7):851-65. Review. PubMed PMID: 27021417. 3. Augusto MT, Hollmann A, Porotto M, Moscona A, Santos NC. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length. Molecules. 2017 Jul 15;22(7). pii: E1190. doi: 10.3390/molecules22071190. PubMed PMID: 28714870; PubMed Central PMCID: PMC5776016. 4. Tuma R, Russell M, Rosendahl M, Thomas GJ Jr. Solution conformation of the extracellular domain of the human tumor necrosis factor receptor probed by Raman and UV-resonance Raman spectroscopy: structural effects of an engineered PEG linker. Biochemistry. 1995 Nov 21;34(46):15150-6. PubMed PMID: 7578129. |
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
CAS No.: 2055042-82-3
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence.
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