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Fluphenazine free base

CAS No.: 69-23-8

Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine wo
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Description Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine works by blocking postsynaptic dopamine D2 receptors in the limbic system, cortical system, and basal ganglia. This prevents the effects of dopamine, which reduces the hallucinations and delusions associated with schizophrenia.
Synonyms Siqualine, Fluphenazine, Fluorophenazine, Fluorphenazine, Triflumethazine, Fluorfenazine
molecular weight 437.52
Molecular formula C22H26F3N3OS
CAS 69-23-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
References 1. Xu F, Xia Y, Feng Z, Lin W, Xue Q, Jiang J, Yu X, Peng C, Luo M, Yang Y, Wei Y, Yu L. Repositioning antipsychotic fluphenazine hydrochloride for treating triple negative breast cancer with brain metastases and lung metastases. Am J Cancer Res. 2019 Mar 1;9(3):459-478. eCollection 2019. PubMed PMID: 30949404; PubMed Central PMCID: PMC6448056. 2. Menilli L, García-Argáez AN, Dalla Via L, Miolo G. The neuroleptic drug fluphenazine induces a significant UVA-mediated cytotoxic effect on three human cancer cell lines through apoptosis. Photochem Photobiol Sci. 2019 Mar 12. doi: 10.1039/c9pp00023b. [Epub ahead of print] PubMed PMID: 30860541. 3. Otręba M, Beberok A, Wrześniok D, Buszman E. In vitro melanogenesis inhibition by fluphenazine and prochlorperazine in normal human melanocytes lightly pigmented. Daru. 2018 Sep;26(1):85-89. doi: 10.1007/s40199-018-0206-4. Epub 2018 Jul 24. PubMed PMID: 30159761; PubMed Central PMCID: PMC6154481. 4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK500732/ PubMed PMID: 29999791.