| Description | Fluperamide is an antidiarrheal. |
| Synonyms | R18910, R 18910, R-18910 |
| molecular weight | 545.04 |
| Molecular formula | C30H32ClF3N2O2 |
| CAS | 53179-10-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Megens AA, Canters LL, Awouters FH, Niemegeers CJ. Normalization of small intestinal propulsion with loperamide-like antidiarrheals in rats. Eur J Pharmacol. 1990 Mar 27;178(3):357-64. PubMed PMID: 2340864. 2. Reynolds IJ, Gould RJ, Snyder SH. Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects. J Pharmacol Exp Ther. 1984 Dec;231(3):628-32. PubMed PMID: 6502516. 3. Farrington H, Mendelsohn F, Chan S, Reinlib L, Guggino SE. Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids. J Pharmacol Exp Ther. 1994 Nov;271(2):1074-9. PubMed PMID: 7525935. |