| Description | Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telangiectasia. |
| Synonyms | Locacorten, NSC-107680, 特戊酸氟米松, Lorinden, NSC 107680, NSC107680, Locorten |
| molecular weight | 494.57 |
| Molecular formula | C27H36F2O6 |
| CAS | 2002-29-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 22.5 mg/mL (45.49 mM) |
| References | 1. Scaglione F, et al. Flumethasone pivalate (Locorten) in the treatment of oral diseases. Drugs Exp Clin Res. 1985;11(8):523-6. 2. Wienert V, Blazek V. [Effect of salicylic acid on the blanching effect of flumethasone pivalate (author's transl)]. Arch Dermatol Res. 1981;271(1):19-27. German. 3. Abdel-Aleem EA, et al. Novel spectrophotometric determination of flumethasone pivalate and clioquinol in their binary mixture and pharmaceutical formulation. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt B:707-13. 4. Hojyo T. Combination dermatological products: a comparison of betamethasone dipropionate/clotrimazole/gentamicin sulphate and flumethasone pivalate/clioquinol creams. J Int Med Res. 1987 Sep-Oct;15(5):255-63. |