| Description | FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. This compound displays significant antiproliferative effects against MV4-11 cells and Ba/F3 cell lines expressing mutant FLT kinase variants, such as FLT-D835Y and FLT3-F691L [1]. |
| molecular weight | 426.47 |
| Molecular formula | C24H22N6O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |