| Description | Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure. |
| molecular weight | 239.27 |
| Molecular formula | C11H10FNO2S |
| CAS | 76568-02-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4 mg/mL (16.72 mM) |
| References | 1. M Yano, et al. Effects of balanced vasodilator, flosequinan, on aortic impedance in failing heart. J Cardiovasc Pharmacol. 1998 Sep;32(3):466-70. 2. P G Cavero, et al. Flosequinan, a new vasodilator: systemic and coronary hemodynamics and neuroendocrine effects in congestive heart failure. J Am Coll Cardiol. 1992 Dec;20(7):1542-8. 3. E Kashiyama, et al. Chiral inversion of drug: role of intestinal bacteria in the stereoselective sulphoxide reduction of flosequinan. Biochem Pharmacol. 1994 Jul 19;48(2):237-43. 4. M F Sim, et al. Cardiovascular effects of the novel arteriovenous dilator agent, flosequinan in conscious dogs and cats. Br J Pharmacol. 1988 Jun;94(2):371-80. PubMed PMID: 3293682; PubMed Central PMCID: PMC1854003. |