| Description | Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM. It effectively reduces wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1]. |
| Synonyms | TAK-994 |
| molecular weight | 497.53 |
| Molecular formula | C22H25F3N2O4S.3/2H2O |
| CAS | 2861934-86-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |