| Description | FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitters (FFNs) targeting neuronal vesicular monoamine transporter 2 (VMA T2).FFN 511 hydrochloride inhibits the binding of 5-hydroxytryptamine to VMA T2-containing membranes and can be used for labelling of dopaminergic nerve endings in acute slices of in vivo cortex-striatum. The excitation and emission maxima are 406 and 501 nm, respectively. |
| In vitro | FFN511(350 nM；30分钟)在培养的小鼠嗜铬细胞中以与 LDCVs 一致的模式积累，并且这种积累被亲脂性碱氯喹所消除[2]。 |
| Synonyms | FFN 511 hydrochloride(1004548-96-2 Free base) |
| molecular weight | 320.81 |
| Molecular formula | C17H21ClN2O2 |
| CAS | 2596358-28-8 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Keighron JD, et al. Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods. Analyst. 2012 Apr 21;137(8):1755-63. 2. Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324(5933):1441-4. |