| Description | Fet F-18 is an amino acid analog radiolabeled with fluorine F-18, a positron-emitting isotope, can be used as a tracer in positron emission tomography (PET). |
| Synonyms | Fet F18, 18F-Fluoroethyltyrosine, 18F-FET |
| molecular weight | 226.23 |
| Molecular formula | C11H14FNO3 |
| CAS | 178433-03-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Schwartz JC, Cech TR, Parker RR. Biochemical Properties and Biological Functions of FET Proteins. Annu Rev Biochem. 2015;84:355-79. doi: 10.1146/annurev-biochem-060614-034325. Epub 2014 Dec 8. Review. PubMed PMID: 25494299. 2. Misch M, Guggemos A, Driever PH, Koch A, Grosse F, Steffen IG, Plotkin M, Thomale UW. (18)F-FET-PET guided surgical biopsy and resection in children and adolescence with brain tumors. Childs Nerv Syst. 2015 Feb;31(2):261-7. doi: 10.1007/s00381-014-2552-y. Epub 2014 Sep 18. PubMed PMID: 25231277. 3. Habermeier A, Graf J, Sandhöfer BF, Boissel JP, Roesch F, Closs EI. System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET). Amino Acids. 2015 Feb;47(2):335-44. doi: 10.1007/s00726-014-1863-3. Epub 2014 Nov 11. PubMed PMID: 25385314. 4. Nedergaard MK, Michaelsen SR, Urup T, Broholm H, El Ali H, Poulsen HS, Stockhausen MT, Kjaer A, Lassen U. 18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma. PLoS One. 2015 Feb 13;10(2):e0115315. doi: 10.1371/journal.pone.0115315. eCollection 2015. PubMed PMID: 25680186; PubMed Central PMCID: PMC4332497. |