Description | Feeblin(IRF5-IN-1) is a protein degradation inducer that specifically blocks pro-inflammatory signaling pathways associated with autoimmune diseases and can be used to study immune system disorders in the class of systemic lupus erythematosus. |
Synonyms | IRF5-IN-1 |
molecular weight | 431.57 |
Molecular formula | C27H33N3O2 |
CAS | 689270-18-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 50 mg/mL (115.86 mM) |
References | 1. Boeszoermenyi A,et al. A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. Nat Commun. 2023 Oct 20;14(1):6626. |